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What is Oxytocin?

Oxytocin is a mammalian neurohypophysial hormone. Produced by the hypothalamus and stored and secreted by the posterior pituitary gland, oxytocin acts primarily as a neuromodulator in the brain. Oxytocin is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, maternal bonding, а также, after stimulation of the nipples, lactation. Both childbirth and milk ejection result from positive feedback mechanisms.

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Oxytocin Usage

1) Oxytocin is used in veterinary medicine to facilitate birth and to stimulate milk release
2) Oxytocin analogues are used for labor induction and to support labor in case of difficult parturition. It has largely replaced ergometrine as the principal agent to increase uterine tone in acute postpartum hemorrhage.

Oxytocin Dosage:

Oxytocin intravenous drip, once the 2.5 – 5 units, with Sodium Chloride Injection diluted to each 1ml contains 0.01 units. Intravenous drip of the beginning of every minute of not more than 0.001 в 0.002 units, each 15 – 30 minutes increased 0.001 в 0.002 units, to achieve the contractions and normal childbirth is similar, the fastest per minute of not more than 0.02 units, usually 0.002 в 0.005 units per minute.

Control postpartum hemorrhage per minute intravenous drip of 0.02 – 0.04 units, expulsion of the placenta after intramuscular injection of 5 в 10 units.

Lactogenic just before a 2 – 3 минут, with nasal drops a 3 drop, drop into one side or both sides of the nostril.

Oxytocin Basic Information